1993: Nature publishes results from JK Douglass on the impact of stochastic resonance on individual neurons.
1995: Use of stochastic resonance to boost neurons in biological systems was further discussed by Moss .
1999: In Science, neurobiologists identified a region of the brain capable of generating respiratory rhythm.
1999: Koshiya and Smith link pacemaker neurons to rhythmic breathing (Nature).
2012: Fernando Pena Ortega discussed the specific pacemaker neurons responsible for breathing.
2015: Dr. David Paydarfar applied stochastic resonance using SVS to help preemies breathe and published results in Pediatrics.
2017: In April 2017, Elizabeth Bloch-Salisbury's work with SVS with opioid-exposed newborns was published in PLOS ONE.
2019: Prapela's SVS hospital bassinet pad is designated as a breakthrough device by the FDA
Version 1.0: Was developed at Harvard's Wyss Institute for Biologically Inspired Engineering and the University of Massachusetts Medical Center and Massachusetts General Hospital. For over 10 years a multi-disciplinary team worked on SVS for infant health.
Version 2.0: Working with the Wyss Institute and our partners, Prapela improved the quality of SVS with state of the art components and production methods. The advanced electronics in our hand-held controller precisely governs the gentle, random vibration, replicating the performance of V1.0. Our proprietary test methods ensures the gentle vibration meets exact specifications on every unit we ship.
Prapela SVS is covered with three (3) patents in the United States and abroad. The 1st patent was issued by the US Patent & Trademark Office on April 9, 2019. SVS patents broadly cover the application of improving cardiorespiratory function and reducing irritability in infants. The patents were developed at Harvard's Wyss Institute of Biologically Inspired Engineering, the University of Massachusetts, and Massachusetts General Hospital and were exclusively licensed by Prapela, Inc. "Prapela" is a registered trademark of Prapela, Inc.